19 CHEMICALS KNOWLEDGE HUB Issue 1 / July 2025 SUNRESIN Current stabilisation practices focus on reducing haze by targeting its main precursors: polyphenols and proteins. One common method involves using PVPP, an adsorbent with strong affinity for polyphenols. While effective, excessive PVPP can remove beneficial polyphenols critical for flavour and antioxidant properties. Silica-based adsorbents help with protein-induced haze, but lack selectivity and are often used alongside PVPP9. Alternatively, enzymatic stabilisation hydrolyses haze-sensitive proteins, but it may require additional techniques to tackle polyphenol-induced haze effectively10. Chromatographic materials, such as those incorporating cross-linked PVP on engineered supports, have shown promising results in beer stabilisation, with polyphenol adsorption rates reaching 34-55%, and good regeneration properties, offering a sustainable solution for beer stabilisation11. Effective beer stabilisation must balance sensory and functional properties for long-term stability. Over-treatment can deplete essential flavour and antioxidant compounds, while under-treatment may cause colloidal instability. Combining stabilisation techniques with precise brewing process control ensures optimal product quality and extended shelf life12,13. Discussion Sunresin’s innovative PVP-functionalised resin, Seplife® K602FF/CSS3.0, marks a significant advancement in brewing stabilisation technology, offering numerous advantages, including cost savings, scalability, and rapid implementation compared to other PVPP solutions. At its core, Seplife K602FF/CSS3.0 was developed using patented advanced cross-linking and functionalisation technologies14 for optimal performance of the PVP active groups (Figure 1). Sunresin’s methodology created an effective binding matrix for targeting polyphenols in beer, with minimal undesired interactions. Table 1 shows the characteristics of the Seplife K602FF/CSS3.0. The resin appears as perfect spherical beads that can be easily packed in any chromatography system (Figure 2). A contact time of a few seconds is enough to retain beer polyphenols by adsorption, which are then removed from the resin during regeneration. Neither substances are dissolved in the beer nor particles released to the beer during the beer stabilisation treatment. A key performance characteristic of Seplife K602FF/CSS3.0 is its stability for a minimum of 1,000 polyphenol removal cycles, along with the corresponding cleaning-in-place (CIP) and sanitisation steps. Figure 3 shows the results obtained in forced ageing conditions performed using the resin packed in chromatography column treated with commercially available Snow beer (Snowflake Brewing) at a contact time of <1min, followed by 45 min CIP treatment with 1M NaOH after each cycle. The resin maintained its initial polyphenol removal capacity up to the final test. Figure 1. Chemical structure of Seplife® K602FF/CSS3.0. Table 1. The properties of the chromatographic resin Seplife K602FF/CSS3.0. *Test conditions: 26/300mm column, height 20cm, mobile phase: water. Figure 2. Microscope picture of the Seplife K602FF/ CSS3.0 beads.
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