32 CHEMICALS KNOWLEDGE HUB Issue 1 / July 2025 reduction in blood glucose spikes after meals when participants consumed Nextida GC before eating. This could indicate a more stable metabolic response and reduced likelihood of experiencing the typical post-meal crash. Additionally, improvements were noted in insulin response. Participants had higher insulin levels before meals and a faster return to baseline levels afterward, pointing to more efficient glucose metabolism. In total, Nextida GC reduced post-meal glucose spikes by an average of 42% in the full study population, demonstrating its potential as a practical tool for post-meal blood sugar management in everyday settings. As part of a broader shift toward proactive health management, ingredients like Nextida GC reflect a new direction in nutrition towards targeted, research-backed formulations that work with the body’s existing systems to support wellbeing. For healthy individuals looking to support their metabolic wellness without resorting to pharmaceutical options, specific collagen peptide compositions like Nextida GC could offer a compelling, natural solution. References 1. SPINS - 2024 Trend Predictions 2. Meltwater – Keyword “GLP-1” – 2023 vs. 2024 3. MarkWide Research, Metabolic Disease Treatment Market Analysis, 2025-2034. 4. FMCG Gurus, 2022 5. Gangwisch et al., (2020) High glycemic index and glycemic load diets as risk factors for insomnia: analyses from the Women’s Health Initiative, The American Journal of Clinical Nutrition, Volume 111, Issue 2, Pages 429-439, ISSN 0002-9165, https://doi.org/10.1093/ajcn/ nqz275. 6. Hall et al. (2018) Glucotypes reveal new patterns of glucose dysregulation. PLOS Biology 16(7): e2005143. https://doi.org/10.1371/ journal.pbio.2005143 7. Giri et al., (2018) Chronic hyperglycemia mediated physiological alteration and metabolic distortion leads to organ dysfunction, infection, cancer progression and other pathophysiological consequences: An update on glucose toxicity, Biomedicine & Pharmacotherapy, Volume 107, Pages 306-328, ISSN 0753-3322, https://doi. org/10.1016/j.biopha.2018.07.157 8. Ibid 9. Blaak et al., (2012) Impact of postprandial glycaemia on health and prevention of disease. Obesity Reviews, 13: 923-984. https://doi. org/10.1111/j.1467-789X.2012.01011.x 10. Shauna at al (2003) Prolongation of Satiety After Low Versus Moderately High Glycemic Index Meals in Obese Adolescents. Pediatrics; 111 (3): 488–494. 1https://doi.org/10.1542/ peds.111.3.488 11. Ludwig et al., (1999) High Glycemic Index Foods, Overeating, and Obesity. Pediatrics; 103 (3): e26. https://doi.org/10.1542/peds.103.3.e26 12. Brand-Miller et al., (2002) Glycemic index and obesity, The American Journal of Clinical Nutrition, Volume 76, Issue 1, Pages 281S-285S, ISSN 0002-9165, https://doi.org/10.1093/ ajcn/76.1.281S 13. Jiang et al, 2014, Collagen Peptides improve knee osteoarthritis in elderly women – a 6 month randomized, double-blind, placebo-controlled study, Agro Food Industry Hi Tech 14. Pappelbaum et al., Revealing novel insights on how oral supplementation with collagen peptides may prevent hair loss: Lessons from the human hair follicle organ culture, Journal of Functional Foods, Volume 116, 2024, 106124, ISSN 1756-4646,https://doi.org/10.1016/j. jff.2024.106124. 15. Asserin, J., et al. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebocontrolled clinical trials. Journal of Cosmetic Dermatology. 2015. https://doi.org/10.1111/ jocd.12174 16. Seino, Y., M. Fukushima, and D. Yabe, GIP and GLP-1, the two incretin hormones: Similarities and differences. J Diabetes Investig, 2010. 1(1-2): p. 8-23. https://doi.org/10.1111/j.20401124.2010.00022.x 17. Grasset, E., et al. (2024) A Specific Collagen Hydrolysate Improves Postprandial Glucose Tolerance in Normoglycemic and Prediabetic Mice and in a First Proof of Concept Study in Healthy, Normoglycemic and Prediabetic Humans. Food Sci Nutr, 12: 9607-9620. https:// doi.org/10.1002/fsn3.4538 ROUSSELOT FLORENCIA MORENO TORRES Global Marketing Manager ROUSSELOT
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