EUROAPI to Acquire BianoGMP to Strengthen its CDMO Expertise in the High-Growth oligonucleotide Market

EUROAPI and the shareholders of BianoGMP, a CDMO, with recognized expertise in oligonucleotides, have signed a share purchase and transfer agreement under which EUROAPI will acquire 100% of Biano shares. The total consideration for the transaction is approximately €10 million, including the acquisition price (upfront payment and deferred consideration) and Capex aimed to increase Biano’s capacity to address larger scale and more complex projects. The closing of the transaction is subject to customary conditions precedent and is expected in the fourth quarter of 2023. It will have limited impacts on EUROAPI’s 2023 financial performance.

Created in 2017 by Prof. Tobias Pöhlmann and Dr. Rolf Günther, Biano is an oligonucleotide CDMO player focused on small-scale, early-stage (pre-clinical to phase 1), complex and customized projects, with a diversified client base in Europe and Asia. Biano is located in Gera, Germany.

This acquisition will strengthen EUROAPI’s CDMO market position in oligonucleotides by adding to its current offer a reputable oligonucleotide CDMO pure player, with capacity to grow. The planned expansion of EUROAPI’s Frankfurt oligonucleotide capacity in 2025 will be complementary to Biano’s early-phase expertise and enable larger-scale projects offering. In addition to opening opportunities for cross-referral commercial synergies and scientific cooperation, this transaction will further differentiate EUROAPI’s value proposition to accompany a wider client base across the whole oligonucleotide development continuum, from research to commercialization.

Consistent with EUROAPI’s entrepreneurial approach, Biano will retain its corporate brand and become a EUROAPI company.

“The acquisition of Biano builds on EUROAPI’s strategy to accelerate its CDMO roadmap through vertical integration and strengthen its highly differentiated platforms, notably oligonucleotide activity. By coupling Biano’s expertise and capacity in early-stage projects with EUROAPI’s larger scale capabilities, we aim to support our clients along the drug development pathway as a one-stop shop,” said Karl Rotthier, Chief Executive Officer of EUROAPI. “This bolt-on transaction is a key milestone in our journey to become a leading, fast-growing CDMO company.”

“I am thrilled to get the opportunity to continue to expand Biano’s capabilities in order to grow with our customers and provide material for later clinical phases,” said Prof. Tobias Pöhlmann. “Biano has a track record of hands-on support on innovative oligonucleotide developments, complex chemistries and conjugation of peptides and lipids. With a client base in Europe and Asia, it will benefit from EUROAPI’s sales and marketing teams to expand into new geographies.”

Oligonucleotides are large molecules with complex structures which address a wide array of therapeutic applications including oncology, central nervous system conditions, genetic disorders and infectious or metabolic diseases. The global oligonucleotide market is growing between +12% to +14% per year. It is almost entirely outsourced to CDMOs. Approximately 600 molecules are currently being developed in that market, including 500 in preclinical and phase I, and approximately 100 in later phases2.

Oligonucleotides are a priority segment for EUROAPI’s CDMO business. Last year, EUROAPI announced an initial investment of €18 million in new manufacturing equipment that would increase overall peptide and oligonucleotide capacity at its Frankfurt site to approximately 500 kilograms per year by 2025. EUROAPI is currently working on 18 CDMO large molecule projects (including peptides, oligonucleotides, and lipids) as part of a portfolio of 79 projects, as of June 30, 2023.